Supplement analysis backed by scientific evidence · PT

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Limited evidenceImmunity

Shark Liver Oil (Alkylglycerols)

Sold for its alkylglycerol content, with immune and anti-radiation claims dating back to mid-20th-century Scandinavian research. The modern human data concern blood lipids, not immunity.

Evidence last reviewed: August 2026

What the science says

  • Immune claims rest on old and preclinical work Limited evidence

    A review of alkylglycerols from shark liver oil summarised antitumour, antimicrobial and immunostimulant effects reported mostly in cell and animal experiments and in small historical clinical series. No modern randomized trial supports the immune or radiation-protection claims on labels.

  • A modern trial measured lipids, not infections Limited evidence

    A randomized supplementation trial found that shark liver oil raised endogenous plasmalogen levels and lowered some markers of dyslipidemia and inflammation. It had no infection or immune-function endpoint.

Dosage & safety

Studied doseNo dose validated for immune use. Labels typically provide 500–1000 mg of alkylglycerol-rich oil per day.
SafetySome shark liver oils are rich in vitamin A, and chronic excess vitamin A is toxic to the liver and teratogenic — check the label and avoid in pregnancy. Sharks are long-lived predators, so heavy metal and organic contaminant content depends heavily on sourcing and purification. Sustainability is a genuine concern with these products.

Scientific references

Where to buy

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