Supplement analysis backed by scientific evidence · PT

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Limited evidenceBrain & cognition

Oat Straw Extract

Single-dose studies show small improvements in speed of thinking, but the one 12-week trial found nothing at all. Whatever green oat extract does appears to be acute and modest, and there is no evidence it works when taken daily.

What the science says

  • Acute cognitive effects Limited evidence

    In a double-blind, placebo-controlled crossover trial, 37 adults aged 40-65 who felt their memory had declined took single doses of 800 mg or 1600 mg green oat extract (Neuravena) or placebo. The 800 mg dose increased overall speed of performance across timed tasks and improved delayed word recall errors and an executive-function task; 1600 mg was not better. Many endpoints were tested at multiple time points, which inflates the chance of false positives.

  • Daily supplementation does not work Limited evidence

    A 12-week randomized, double-blind, placebo-controlled crossover trial gave 1500 mg/day to 37 healthy adults aged about 67. Chronic supplementation did not affect any measure of cognition, including Stroop, letter cancellation, rule-shift, multi-tasking and trail-making. The authors concluded the acute benefit does not persist with regular treatment.

  • Libido and "free testosterone" claims Limited evidence

    Oat straw is widely marketed as freeing bound testosterone or boosting libido. There are no controlled human trials supporting this; the claim traces back to uncontrolled 1980s observations and has never been tested properly.

Dosage & safety

Studied doseStudied doses are 800-1600 mg of standardized wild green oat extract (Neuravena) as a single dose, with 800 mg appearing at or near the optimum, and 1500 mg/day in the 12-week trial that showed no effect. Generic "oat straw" powders and teas are a different preparation entirely and have not been tested.
SafetyNo safety signals emerged in the trials; oat products are food-grade and very well tolerated. People with coeliac disease should note that oats are frequently cross-contaminated with wheat and barley gluten during processing and that a minority of coeliacs react to avenin itself, so choose certified gluten-free products. Oat extracts contain small amounts of beta-glucan and may mildly lower glucose and LDL cholesterol. No known drug interactions and no data in pregnancy. Not prohibited in sport.

Scientific references

Where to buy

Life Extension, Dopa-Mind™, 60 Vegetarian Tablets

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