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Limited evidencePhysical performance

Creatine Nitrate

Creatine paired with nitrate for solubility and a nitric-oxide angle. It appears safe at the doses tested, but no better than creatine monohydrate on any measured outcome.

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What the science says

  • Tolerated up to 3 g/day Moderate evidence

    A dose-dependent randomised trial of acute and 28-day creatine nitrate supplementation found it well tolerated up to 3 g/day, with no clinically significant changes in blood markers.

  • No clear performance advantage Limited evidence

    The same trial found limited effects on exercise performance, and a systematic review of alternative creatine forms found no evidence that any of them outperforms monohydrate.

  • The nitrate dose is too small to matter Limited evidence

    The nitrate delivered by these products is far below the amounts used in beetroot-juice nitrate trials, so the vascular rationale does not carry over.

Dosage & safety

Studied doseStudied at 1–3 g/day of creatine nitrate. Reaching a standard 3–5 g creatine dose would require considerably more than typical label servings.
SafetyTolerated in the one trial that tested it; higher doses are unstudied. Standard creatine cautions apply. People taking nitrates for angina or PDE5 inhibitors should be cautious with any added nitrate.

How to take it

TimingTiming does not matter for creatine loading; nitrate-based products are usually taken before training out of habit rather than evidence.
With food?With or without food.
Worth knowingScaling this up to a proper 3–5 g creatine dose also scales the nitrate load, which is exactly why plain monohydrate is the safer buy.

Interactions

With medications

  • nitrates for angina and PDE5 inhibitors such as sildenafil

    Added dietary nitrate can deepen the blood pressure drop. do not combine without asking your doctor

  • blood-pressure medication

    Nitrate has a mild additive blood pressure lowering effect. monitor your blood pressure when you start

With other supplements

  • beetroot juice or other nitrate products

    Nitrate loads add together. do not stack nitrate sources

Well-established interactions only — this is not a complete list. Always tell your doctor and pharmacist what you take.

Frequently asked questions

Is creatine nitrate better than creatine monohydrate?

No, creatine nitrate has shown no clear performance advantage over creatine monohydrate, and a systematic review found no alternative creatine form outperforms monohydrate. The evidence for creatine nitrate's benefits is limited.

Is creatine nitrate safe?

A randomised trial found creatine nitrate well tolerated up to 3 g/day for 28 days with no clinically significant changes in blood markers, which is moderate evidence. Higher doses are unstudied.

Does the nitrate in creatine nitrate boost blood flow?

The nitrate in creatine nitrate is far below the amounts used in beetroot-juice trials, so the vascular rationale does not carry over. Scaling up to a 3–5 g creatine dose also raises the nitrate load, which is why plain monohydrate is the safer buy.

Can I take creatine nitrate with sildenafil?

Do not combine creatine nitrate with nitrates for angina or PDE5 inhibitors such as sildenafil without asking your doctor, as the added nitrate can deepen the blood pressure drop. Also avoid stacking creatine nitrate with beetroot juice or other nitrate products.

Scientific references

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