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Comparison guide

Curcumin, omega-3 or boswellia for inflammation?

"Inflammation" is too vague to shop for: the evidence for each of these is tied to a specific outcome. Curcumin and boswellia have moderate evidence for osteoarthritis pain, while omega-3's strongest evidence is for lowering triglycerides, not for general anti-inflammatory effects. Pick by the problem you actually have.

The options, compared

OptionEvidenceBest forThe honest note
Curcumin (Turmeric extract) Moderate evidence Osteoarthritis joint pain About 1,000 mg/day reduced arthritis pain versus placebo in a meta-analysis, though the trials are short and mostly small. Plain curcumin is poorly absorbed, so choose an enhanced formulation, and take care with gallstones or blood thinners. View
Omega-3 (EPA/DHA) Moderate evidence Triglycerides, not joint pain Its strong evidence is for lowering triglycerides at 2–4 g/day of EPA/DHA; none of its graded claims covers joint pain or general inflammation. High doses may slightly raise the risk of bleeding and atrial fibrillation. View
Boswellia Serrata Moderate evidence Knee osteoarthritis pain and stiffness AKBA-enriched extracts at 100–250 mg/day showed small-to-moderate gains in knee pain, stiffness and function, but the trials are small, mostly manufacturer-funded and heterogeneous. Evidence for asthma or bowel disease is limited; avoid it in pregnancy and be cautious with warfarin or ciclosporin. View

Our verdict

For knee or joint osteoarthritis pain, an enhanced curcumin or an AKBA-standardised boswellia are the reasonable options, both with moderate but uncertain evidence; stop if nothing changes. Take omega-3 for triglycerides or general health, not as a joint-pain remedy. If you are on blood thinners, check with a clinician before taking any of the three.