Supplement analysis backed by scientific evidence · PT

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Limited evidenceVitamins & minerals

Chromium Polynicotinate

Niacin-bound chromium sold for blood sugar and cravings. Chromium as a class produces small, inconsistent glycaemic changes in people with diabetes, and this particular form has barely been studied on its own.

Evidence last reviewed: August 2026

What the science says

  • Small glycaemic changes in type 2 diabetes Limited evidence

    A systematic review and meta-analysis of randomized trials found chromium supplementation modestly reduced fasting glucose and HbA1c in people with type 2 diabetes, with high heterogeneity between studies. Effects in people without diabetes are not established.

  • Little effect on body composition Limited evidence

    A dose-response systematic review and meta-analysis of randomized trials in type 2 diabetes found minimal effects of chromium on body weight and composition. Appetite and craving claims are not supported by this evidence.

  • The polynicotinate form is barely studied Limited evidence

    One randomized trial in hypercholesterolaemic children found low-dose chromium polynicotinate affected lipids only when combined with glucomannan. Almost all other chromium research uses picolinate or chloride, so form-specific claims are unsupported.

Dosage & safety

Studied doseTrials of chromium generally used 200–1,000 µg/day of elemental chromium. Adequate intake for adults is 25–35 µg/day, which diet normally covers.
SafetyUsually well tolerated, but case reports link high-dose chromium supplements to liver injury, kidney problems and acute pancreatitis. The niacin component can cause flushing. Avoid high doses in kidney or liver disease, and monitor glucose closely if you take diabetes medication, since additive effects are possible.

Scientific references

Where to buy

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