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Comparison guide

Spirulina or phycocyanin?

Phycocyanin is the blue pigment-protein extracted from spirulina and sold as a concentrated antioxidant. The human trials that exist were mostly done with whole spirulina, which is not the same product.

The options, compared

OptionEvidenceBest forThe honest note
Spirulina Moderate evidence Lipids and blood pressure Small trials at 1–8 g/day show lipid and blood-pressure improvements, graded moderate because the trials are small, short and from a few groups. View
Phycocyanin Limited evidence Not worth the premium Its human data are one safety study and trials of whole spirulina, so there is no efficacy-based dose. View

Our verdict

Whole spirulina powder is the cheaper and better-studied choice; phycocyanin charges a large premium for little human data. With either, buy third-party tested product, avoid both with phenylketonuria, and never rely on spirulina for B12.