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Limited evidenceGut health

Trikatu

An Ayurvedic mix of black pepper, long pepper and ginger used as a digestive and as a bioenhancer. Its human evidence amounts to reviews and a trial that so far exists only as a published protocol.

Evidence last reviewed: August 2026

What the science says

  • Digestive and flu-like illness use Limited evidence

    A narrative review of Trikatu for flu-like illness collected traditional and preclinical support but identified no controlled clinical trial. The digestive use rests on tradition rather than data.

  • Enhancing absorption of other compounds Limited evidence

    The rationale is that its piperine content increases absorption of other substances, an effect demonstrated for curcumin in human volunteers. That finding belongs to isolated piperine and has not been shown for the Trikatu formula itself.

  • Metabolic effects Limited evidence

    A randomized, double-blind, placebo-controlled trial in dyslipidaemia has been registered and its protocol published, but no results are available yet. Earlier work is limited to network pharmacology and animal models.

Dosage & safety

Studied doseTraditional dose is 250–1000 mg of the powder with meals. No trial-established dose exists.
SafetyPeppery and irritating: heartburn, gastritis and worsening reflux or ulcers are the main issues. Piperine raises blood levels of many drugs, a real interaction risk with anything that has a narrow safety margin. Avoid in pregnancy and with active peptic ulcers.

Scientific references

Where to buy

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