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Limited evidenceLongevity & antioxidants

Myricetin

A flavonol found in berries, walnuts and tea, studied for glucose control and antioxidant effects. The entire evidence base is preclinical; no human trial of myricetin supplementation has been published.

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What the science says

  • Glucose and metabolic effects Limited evidence

    A 2025 review of myricetin's pharmacology describes antidiabetic, antioxidant and anti-inflammatory activity across cell and rodent studies, including improved insulin sensitivity in diabetic animal models. No randomized human trial has tested these outcomes.

  • Anti-inflammatory effects in arthritis Limited evidence

    An experimental arthritis study in rodents reported that myricetin reduced inflammatory signalling and oxidative stress markers. Animal arthritis models frequently fail to predict human results.

Dosage & safety

Studied doseNo human dose established. Supplements commonly supply 50–200 mg/day as a label dose. Bioavailability of oral myricetin is poor and it is rapidly conjugated.
SafetyNo human safety trials. Myricetin inhibits several CYP450 enzymes in vitro and has shown pro-oxidant behaviour at high concentrations, so interaction with medication is a theoretical concern. Avoid in pregnancy, breastfeeding, and alongside anticoagulants without medical advice.

How to take it

TimingTiming does not matter.
With food?Take it with a meal containing fat, which improves flavonol absorption.
Worth knowingOral myricetin is poorly absorbed and rapidly conjugated, so the blood levels behind the laboratory findings are not reachable from a capsule.

Frequently asked questions

Does myricetin help blood sugar or diabetes?

Myricetin improved insulin sensitivity in diabetic animal models, but no randomized human trial has tested it. The evidence is limited and entirely preclinical.

How much myricetin should I take?

Myricetin has no established human dose; supplements commonly supply 50–200 mg/day as a label dose. Oral myricetin is poorly absorbed and rapidly conjugated, so lab-study concentrations are not reachable from a capsule.

Is myricetin safe?

Myricetin has no human safety trials. It inhibits several CYP450 enzymes in lab studies and can act as a pro-oxidant at high concentrations, so avoid it in pregnancy, breastfeeding, and with anticoagulants unless your doctor agrees.

Scientific references

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