Albizia (Mimosa Bark)
Known in Chinese medicine as the 'collective happiness bark' and used for low mood and disturbed sleep. The pharmacological literature is entirely preclinical — no randomised trial in humans has been published.
Evidence last reviewed: August 2026
What the science says
- Antidepressant-like activity Limited evidence
A review of the molecular basis of Albizia julibrissin in depression describes consistent antidepressant-like effects in rodent behavioural models, with proposed serotonergic and neurotrophic mechanisms. Human clinical data are limited to traditional multi-herb formulas rather than controlled trials of the bark itself.
- Sedative and anxiolytic effects Limited evidence
A pharmacological review of substances derived from Albizia julibrissin summarises sedative, anxiolytic and neuroprotective activity attributed to its saponins and flavonoids, all demonstrated in cell and animal systems. No sleep outcome has been measured in people.
- Bark versus flower preparations Limited evidence
A comparative review of Hehuan flowers and Hehuan bark notes that the two parts have overlapping but distinct constituent profiles and traditional indications. Products sold as 'mimosa bark' may not match the material used in any given study.
Dosage & safety
Scientific references
- Molecular basis and mechanism of action of Albizia julibrissin in depression treatment and clinical application of its formulae
- Pharmacological Spectrum of Substances Derived from Albizia julibrissin Durazz
- A comparison review of Hehuan flowers and Hehuan bark on the traditional applications, phytochemistry and pharmacological effects
Where to buy
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