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Moderate evidenceHeart & metabolic

Tomato Extract (Fruitflow)

A water-soluble tomato concentrate that makes platelets less sticky. The antiplatelet effect is reproducible in randomised trials; whether it prevents any clinical event has never been tested.

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What the science says

  • Reduced platelet aggregation Moderate evidence

    A randomised controlled trial comparing the extract with 75 mg aspirin in healthy subjects found measurable inhibition of platelet aggregation, weaker than aspirin but consistent. A four-week randomised crossover trial in middle-aged and older adults found the same direction of effect.

  • Small blood pressure reduction Limited evidence

    A randomised, placebo-controlled crossover study in pre-hypertensive men reported modest reductions in blood pressure. This is a single small trial.

  • No clinical outcome data Limited evidence

    No trial has tested whether the extract reduces heart attacks, strokes or mortality. The approved health claim covers platelet function only.

Dosage & safety

Studied dose150–300 mg/day of the water-soluble tomato concentrate. Effects on platelet function appear within hours and fade over roughly 12–18 hours, so daily dosing is used.
SafetyWell tolerated. Because it inhibits platelets, use caution alongside aspirin, clopidogrel or anticoagulants, and stop before surgery. It is not a replacement for prescribed antiplatelet therapy.

How to take it

TimingTake it at the same time each day, since the platelet effect appears within hours and fades over roughly 12–18 hours.
With food?With or without food; it is water-soluble and does not need fat.
Worth knowingBecause it wears off within a day, missing doses removes the effect entirely rather than just weakening it.

Interactions

With medications

  • aspirin, clopidogrel and other antiplatelet drugs

    It inhibits platelet aggregation itself, so the effects add together. do not add it to prescribed antiplatelet therapy without asking your doctor

  • warfarin and DOACs

    Additive bleeding risk from platelet inhibition on top of anticoagulation. tell your doctor before combining and stop it before surgery or dental work

With other supplements

  • fish oil, garlic, ginkgo

    Antiplatelet effects stack. avoid combining several around surgery

Well-established interactions only — this is not a complete list. Always tell your doctor and pharmacist what you take.

Frequently asked questions

Does Fruitflow tomato extract thin the blood?

Fruitflow tomato extract has moderate evidence for making platelets less sticky: randomised trials show consistent inhibition of platelet aggregation, weaker than 75 mg aspirin. Whether tomato extract prevents heart attacks or strokes has never been tested.

How much Fruitflow should I take?

The studied dose of Fruitflow tomato extract is 150–300 mg/day. Its platelet effect appears within hours and fades over roughly 12–18 hours, so take it at the same time every day.

Can I take tomato extract with aspirin or warfarin?

Do not add Fruitflow tomato extract to aspirin, clopidogrel or other prescribed antiplatelet therapy without asking your doctor, since the effects add together. With warfarin or DOACs it raises bleeding risk, so tell your doctor and stop it before surgery or dental work.

Does tomato extract lower blood pressure?

One small placebo-controlled crossover study in pre-hypertensive men reported modest blood pressure reductions with the tomato extract. That is limited evidence from a single trial.

Scientific references

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